It is estimated that at least 2% to 5% of the population suffer from Fibromyalgia, a complex pain condition in some form, and until now there has been a lack of effective treatments. The novel Neuroplasticity program known as “Amygdala and Insula Retraining” was combined with Mindfulness to create 'MAIR', also known as the Gupta Program, and was tested for 8 weeks against a control group engaging in an equivalent amount of relaxation techniques.

The pilot study results found that after just an 8 week intervention, the MAIR group had significantly greater reductions in symptoms and pain, and increases in overall health, compared to the control group.