For 20 years, National Relief Charities has worked to serve the needs of American Indians living on over 75 reservations throughout the Plains and the Southwestern United States. Through a partnership network of more than 1,000 reservation programs, National Relief Charities provides for 300,000 Native Americans each year.

National Relief Charities uses a modernized warehouse and distribution system to deliver over five million pounds of aid to isolated reservations that some charitable organizations have difficulty reaching. National Relief Charities relies on its partners to identify the specific aid a community needs so that the organization can deliver supplies assured to help the people there. Through individual and corporate donations, NRC provides over $30 million in aid a year.