Tris HCl use is a very important biological buffer, which is widely used in biological system diagnosis industry, such as electrophoresis and protein biotechnology. Tris HCl has a pKa of 8.1, which makes it very suitable for biologics formulation.

Tris hydrochloride buffer can be used in a variety of biological applications, including medium, electrophoresis separation and diagnostic reagent formulation. It can provide a stable weak alkaline environment (7.0-9.1), and the pH value of all buffers depends on temperature and concentration. For tris hcl 6.8, tris hcl 7.4, tris hcl ph 9 and tris hcl 1.5 m ph 8.8 buffer, the pH increases by about 0.03 units for every 1℃ increased in temperature and decreases by 0.03-0.05 units for dilute every 10 times.

Properties Of NeoCide® 2-Amino-2-(Hydroxymethyl)-1,3-propanediol Hydrochloride For IVD

Formula: C4H11NO3.HCl

M.W.: 157.6

Packaging Size: 500g, 1.0Kg, 5.0Kg, 12.5Kg, 25Kg

Specification Of NeoCide® 2 Amino 2 Hydroxymethyl 1 3 Propanediol Hydrochloride For IVD

Test Specification

Appearance (Color) White Crystalline Powder

APHA (Color, 1.0M aqueous solution)   ≤20

Solubility (Turbidity, 5% aqueous solution) Clear

Melting point 150-155°C

Assay (Titration by NaOH) ≥99.0%

 Infrared Spectrum Complies Conforms to Structure

pH 1% H2O 4.2-5.0 (25℃)

UV Absorbance 260mm 10% w/w absorbance≤0.03

UV Absorbance 280mm 10% w/w absorbance≤0.03

UV Absorbance 260mm 10% w/w absorbance≤0.05

UV Absorbance 290mm 10% w/w absorbance≤0.05

Loss on drying (105℃ for 3 Hours) WT% ≤0.5%

Sulfated Ash (650℃ for 3 Hours) Wt% ≤0.1%

Heavy Metals Pb ≤5ppm

Iron, Fe ≤5ppm

Biologic Reagent (BR) and Pharma grade can be available as requested, with DNase-Endonuclease/Exonuclease test and DNase –Nickase, Bioburden