Biotika was founded in 1953 as a new manufacturer of Penicillin on the territory of former Czechoslovakia with the aim to meet domestic demand.

From its foundation until 1990, Biotika was a part of the Spofa concern that was a company embracing all pharmaceutical companies in the former Czechoslovakia.

Historical milestones of Biotika are connected with the beginning of the Penicillin G production in 1956 and the Penicillin V production in 1958.

Launching its own research-development site which at the end of the 70‘s obtained the statute of the Research-Development Base, is also connected with the beginning of the penicillins production.

At the beginning of the 60‘s the biotechnological production was extended by Oxytetracycline production and later by the production of Chlortetracycline and Dextrans for the pharmaceutical application.

In 1971 L-Lysine production by biotechnological process was launched and thereby Biotika became the third manufacturer of this essential amino acid in the world.

The manufacturing and business activities of the company gradually expanded into the area of final drug form production, the production of medicated and feed additive premixes.