Chrom-LinX® laboratory scale empty chromatography column is a family of chromatography column designed for simple operation, high pressure resistance and flexible adjustment, which are suitable for process development, process verification, quality testing and preparative small-scale sample purification.

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Features and Benefits of Chrom-LinX® Laboratory Scale chromatography columns empty

User-friendly design: Ergonomically design the components for easy grasping and handling

Clear view: Equipped with a measurement scale of glass tube for easy to predict and reach a predefined bed height and improving process reproducibility

High pressure resistance: compatible with common resins of different particle sizes allowing operation up to 20 bar* (2 MPa, 290 psi) pressure

Various sizes: Glass tubes with inner diameter (i.d.) of 10 mm, 16 mm, 26 mm or 50 mm, and bed height of 200 mm, 400 mm, 700 mm or 1000 mm provide a wide range of column volumes

High flexibility: Equipped with single/double adjustable capital for flexible expansion of column volumes

Easy to clean: Each component for easy assembling removing and cleaning

Compatibility: Supplied with tubing and connectors suitabling for a variety of common laboratory tomographic systems

*The columns withstands pressures up to 7 bar (0.7 MPa, 101.5 psi) with 50 mm inner diameter.

Product Characteristics of Chrom-LinX® Laboratory Scale Empty Chromatography Column

Chrom-LinX® Laboratory Scale Empty Chromatography Columns are available in two designs: single adjustable capital and double adjustable capital. The design of single adjustable capital mainly consists of a adjustable capital, a chromatography column tube and a fixed capital. The design of double adjustable capital replaces the fixed capital with an adjustable capital to extend the column volume (Fig 2).

Chrom-LinX® Laboratory Scale Empty Chromatography Columns are equipped with 10 μm net ring (5 μm net ring being also optional), which are compatible with common resins of different particle sizes.

Chemical Resistance of Chrom-LinX® Laboratory Scale Empty Chromatography Column

Chrom-LinX® laboratory grade empty chromatography columns are made of biocompatible materials with good chemical tolerance. The columns can be used in aqueous solutions and almost all the organic solvents commonly used in liquid chromatography of macromolecules. The columns intolerant of chlorinated hydrocarbons, acetone and other ketones, aliphatic esters, and phenol. The columns are not allowed to use the solution containing more than 2 M NaOH, 1 M HCl, other strong mineral acids, or 75% acetic acid.

Instructions of Chrom-LinX® Laboratory Scale Empty Chromatography Column

Chrom-LinX® laboratory grade empty chromatography column may be used at temperatures from 4° C to 40° C and pressures up to 20 bar (2 MPa, 290 psi) with inner diameters of 10 mm, 16 mm and 26 mm, and 7 bar (0.7 MPa, 101.5 psi) with an inner diameter of 50 mm.

Always clean the column and components with purified water before using.

When packing the column, the double top cap can be rotated, and the threaded shaft moves axially. This operation makes the resins easy to compress. If necessary, column packing can be performed using either a packing tube (Fig 4) or an extra column tube attached with a packing connector.