The number of people with diabetes rose from 151 million in 2000 to 463 million in 2019; by 2045 this number will rise to 700 million. 1 in 5 of the people who are above 65 years old have diabetes, 1 in 2 people (232 million) with diabetes were undiagnosed, and diabetes caused 4.2 million deaths. Diabetes caused at least USD760 billion dollars in health expenditure in 2019 – 10% of total spending on adults. More than 1.1 million children and adolescents are living with type 1 diabetes, and 374 million people are at increased risk of developing type 2 diabetes.

Diabetes is a chronic disease. Diabetes occurs when the pancreas cannot produce enough insulin or the body cannot effectively use the produced insulin (diabetes is a hormone that regulates blood sugar). High blood sugar or elevated blood sugar is a common result of uncontrolled diabetes. Over time, diabetes can seriously damage many systems of the human body, especially nerves and blood vessels, so the prevention and treatment of diabetes is particularly important in our daily life. In fact, the incidence of diabetes in low- and middle-income countries is rising faster than in high-income countries. As the health problems of diabetes threaten people's lives seriously, the prevention of diabetes and the corresponding antidiabetic medications have also attracted more and more attention. As a professional anti-insulin drugs manufacturer, Beilu Pharma can provide you with 2 different types of high-quality oral antidiabetic drugs: glimepiride tablet 1mg, glimepiride 2mg tablets and repaglinide tablets.

Types of antidiabetic medications

Glimepiride Tablets

Glimepiride tablets are sulfonylurea hypoglycemic agents and are suitable for type 2 diabetes. As one of the common antidiabetic drugs, glimepiride tablets have a unique dual mechanism of action, which can promote insulin secretion and improve insulin resistance.

Repaglinide Tablets

Repaglinide tablets are non-sulfonylurea insulin-secreting agents used to treat patients with type 2 diabetes. Repaglinide tablets produced by Beilu Pharma can comprehensively improve the patient's blood glucose control regardless of single-agent or combination therapy.

Types of hypoglycemic drugs

According to the classification criteria proposed by the international general WHO diabetes expert committee, it is mainly divided into type 1 diabetes, type 2 diabetes and gestational diabetes, the most common type of diabetes in the general population is type 2 diabetes.

Type 1 diabetes is a condition in which your immune system destroys insulin-making cells in your pancreas. The condition is usually diagnosed in children and young people, they mainly rely on exogenous insulin supplementation to maintain their lives.

Type 2 diabetes (previously called non-insulin-dependent or adult-onset diabetes) is caused by the body's inability to use insulin effectively. The vast majority of diabetic patients are type 2 diabetes, this type of diabetes is mainly the result of overweight and lack of physical activity. Until recently, this type of diabetes was seen only in adults but it is now also occurring increasingly frequently in children.

Gestational diabetes is characterized by high blood glucose levels during pregnancy. It may occur at any time during pregnancy (although most likely after week 24) and usually disappears after the pregnancy.

Oral Hypoglycemic Drugs In Patients With Type 2 Diabetes And Chronic Kidney Disease

Chronic kidney disease (CKD) is a group of clinical syndromes characterized by long-term abnormalities of kidney structure and renal function. The incidence is increasing and has become a major global public health problem. Type 2 diabetes is often associated with CKD, which has become one of the main causes of death for diabetic patients in China. Glycemic control is essential to delay the development of early CKD. Oral hypoglycemic drugs are one of the most commonly used hypoglycemic drugs.