Irbesartan is an angiotensin II receptor inhibitor, angiotensin II receptors are divided into AT1, AT2. Irbesartan by selectively blocking the AT1 receptor of AnglII, it can inhibit the conversion of AngI into AngII, and can specifically antagonize the ACE 1 receptor (AT1). Irbesartan's antagonistic effect on AT1 is 8500 times that of AT2, which inhibits vasoconstriction and the release of aldosterone by selectively blocking AngII's binding to AT1 receptors, resulting in a hypotensive effect.

Specifications of Irbesartan CAS 138402 11 6

Tests Standard Results

Appearance White to almost white crystalline powder Almost white crystalline powder

Solubility Slighttly soluble in alcohol and in methylene Chloride ,practically insoluble in water qualified

Water ≤0.5% 0.40%

Limit of azide ≤10ppm ＜1ppm

Heavy metals ≤0.002% ＜0.002%

Assay(HPLC) 98.0%~102.0% 99.50%

Parameters of Irbesartan CAS 138402-11-6

Product parameters

Cas number: 138402-11-6

Appearance: White to almost white crystalline powder

Purity: 98~102%

Package details: 25kg/drum

Brand: Fortunachem

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