Cyclophosphamide CAS 50-18-0 Wholesale & Bulk

Cyclophosphamide is a medication used primarily in chemotherapy to treat various types of cancer. It belongs to a class of drugs called alkylating agents, which work by interfering with the growth and spread of cancer cells in the body. Cyclophosphamide can be administered orally or intravenously.

In addition to cancer treatment, cyclophosphamide is also used in the treatment of certain autoimmune diseases, such as lupus nephritis and rheumatoid arthritis. It works by suppressing the immune system, which can help reduce inflammation and prevent the immune system from attacking healthy tissues.

Like all chemotherapy drugs, cyclophosphamide can have side effects, including nausea, vomiting, hair loss, increased risk of infection, and a decrease in blood cell counts. However, its benefits in treating cancer and autoimmune diseases often outweigh these risks when used appropriately under medical supervision.

Specifications of Cyclophosphamide CAS 50-18-0

Description of Cyclophosphamide from Wuhan Fortuna Chemical Co.,Ltd

Basic Information of Cyclophosphamide

Product Name Cyclophosphamide

CAS NO. 50-18-0

Apperance White powder

Assay 99%

Pacakge 1kg/Foil Bag,25kg/Drum/Box

MOQ 1kg

Storage Cool and dry place

Shelf Life 2 Years

Brand Fortunachem

Specifications(COA) of Broad-spectrum anti-tumor API Cyclophosphamide CAS NO 50-18-0 CTX

ITEMS SPECIFICATIONS RESULTS

Appearance A white or almost white crystalline powder Conforms

Solubility Soluble in water, freely soluble in alcohol Conforms

Identification（IR） IR spectrum is comparing with the spectrum of reference standard Conforms

Appearance of solution Solution S is clear and not more intensely coloured than reference Conforms

solution Y6

pH 4.0 ~ 6.0 4.23

Chlorides N.M.T. 330ppm Conforms

Phosphates N.M.T. 100ppm Conforms

Water 6.0%~ 7.0% 6.47%

Related substances Any single impurity N.M.T. 1.0% Conforms

Residual solvents Dichloromethane N.M.T. 600ppm 55ppm

Acetone N.M.T. 5000ppm 102ppm

Triethylamine N.M.T. 5000ppm Not detected

Pyridine N.M.T. 200ppm Not detected

Assay 98.0%~102.0%(on anhydrous basis) 99.21%

Conclusion Conforms to the requirement of EP 10.0

Application of Cyclophosphamide CAS 50-18-0

Cyclophosphamide has several applications primarily in the fields of oncology (cancer treatment) and rheumatology (autoimmune diseases). Here are some of its key applications:

1. Cancer Treatment: Cyclophosphamide is used to treat various types of cancer, including:

- Leukemia

- Lymphoma (e.g., Hodgkin's lymphoma, non-Hodgkin's lymphoma)

- Breast cancer

- Ovarian cancer

- Lung cancer

- Neuroblastoma

- Multiple myeloma

- Sarcomas (e.g., osteosarcoma, soft tissue sarcoma)

- Retinoblastoma (eye cancer)

2. Autoimmune Diseases: Cyclophosphamide is also employed in the treatment of certain autoimmune diseases, where the immune system mistakenly attacks the body's own tissues. These conditions include:

- Lupus nephritis: Kidney inflammation caused by systemic lupus erythematosus (SLE).

- Rheumatoid arthritis: An autoimmune disorder that primarily affects the joints.

- Vasculitis: Inflammation of blood vessels.

- Wegener's granulomatosis: A type of vasculitis affecting the small and medium-sized blood vessels.

3. Bone Marrow Transplantation: Cyclophosphamide is sometimes used in conditioning regimens prior to bone marrow transplantation to suppress the recipient's immune system and prevent rejection of the transplanted marrow.

4. Other Disorders: In addition to cancer and autoimmune diseases, cyclophosphamide may be used off-label or in experimental settings for conditions such as severe systemic sclerosis (scleroderma), severe aplastic anemia, and refractory immune thrombocytopenic purpura (ITP), among others.